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Diabetes Care in Canada and the United States
註釋'Objective'. To determine whether Canadian and American patients who have type 1 diabetes have similar glycemic control. 'Design'. Secondary analysis of a large randomized controlled trial. 'Setting'. Patients screened between 1983 and 1989 for enrolment in the Diabetes Control and Complications Trial (DCCT). 'Patients'. Patients with type 1 diabetes (age 13 to 39) and no major microvascular disease, screened in Canada (n = 245) or the United States (n = 2604). 'Outcome'. Comparison of baseline HbA1c levels of Canadian and American patients. 'Results'. At baseline, mean HbA1c levels were identical in the two countries (8.9 vs. 9.0, p = 0.4). Adjustment for predictors of baseline HbA1c yielded similar findings (9.0 vs. 9.2, p = 0.15). Equal percentages of Canadian and American patients who were screened ultimately entered the DCCT (19% vs. 21%, p = 0.2) and intensive treatment resulted in similar mean levels of HbA1c (7.3 vs. 7.3, p = 0.7). Sociodemographic characteristics that affected baseline HbA1c were generally unrelated to glycemic control during the trial. 'Conclusion'. This analysis suggests that there are no large differences in glycemic control of Canadian and American patients with type 1 diabetes who participated in a large clinical trial.