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Psychoses of the Schizophrenic Spectrum in Twins
Ernst FranzekHelmut Beckmann
其他書名
A Discussion on the Nature - Nurture Debate in the Etiology of “Endogenous” Psychoses
出版Springer Science & Business Media, 2012-12-06
主題Medical / Psychiatry / GeneralPsychology / NeuropsychologyMedical / GeneticsMedical / NeurologyMedical / NeuroscienceMedical / Clinical MedicinePsychology / Physiological PsychologyScience / Life Sciences / Neuroscience
ISBN37091635369783709163535
URLhttp://books.google.com.hk/books?id=0sOLBQAAQBAJ&hl=&source=gbs_api
EBookSAMPLE
註釋Contradictory results in schizophrenia research are generally explained as being due to genetic heterogeneity and multiple factor heredity in relationship to manifold environmental factors. The book reports a short overview of all relevant twin studies on schizophrenic psychoses and provides data and case histories on a systematic twin study based on a polydiagnostic approach carried out by two independently working psychiatrists. In addition to the internationally applied operational diagnostic systems of DSM-III-R and ICD 10 Leonhard’s subclassification of schizophrenic psychoses was used. Up to now this sophisticated methodological approach is unique in the world. The data provide strong evidence that the spectrum of psychoses with schizophrenic and schizophrenia-like symptoms is not a continuum of diseases. At least in Leonhard’s three major groups of cycloid psychoses, unsystematic schizophrenias and systematic schizophrenias genetic, somatic and psycho-social factors play a completely different etiological role. Cycloid psychoses and systematic schizophrenias are predominantly caused by "environmental” factors. In unsystematic schizophrenias, however, genetic predisposition is the main etiological factor and environmental factors are subordinate.