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CLINICAL CHARACTERISTICS OF CARDIOEMBOLIC STROKE WITH OR WITHOUT ATRIAL FIBRILLATION.
註釋Introduction : Devastating cardioembolic (CE) stroke is responsible for approximately 20% of all ischemic strokes. Non-valvular atrial fibrillation(A-fib) is the most frequent cause of CE strokes and is one of the potentially preventable cardiac dysfunction. To reduce the stroke recurrence, besides this ordinary embolic source from A-fib, stroke neurologists have taken into account other causative embolic abnormalities such as tumor fragments, infected and non-infected vegetations, calcified particles and atheromatous debris at the same time. We assumed that there would be a relationship between DWI pattern and cardiac embolism etiology. Therefore, we aimed to investigate clinical and radiological characteristics in CE stroke patients with or without A-fib.Methods : We analyzed the consecutive 1,529 patients from a prospective stroke registry over 4 years. We included the patients who were assigned as CE mechanism in weekly adjudication meeting according to the well-defined TOAST classification. We compared clinical and radiological characteristics between patients with A-fib and without A-fib. We divided A-fib into permanent or persistent, paroxysmal. DWI lesion patterns were categorized to territorial, non-territorial or scattered, borderzone, and subcortical subtypes.Results : In this study, we analyzed a total of 358 stroke patients with CE. As compared to those without A-fib (n=50), those with A-fib (n=308) were older (73.0u00b111.2 vs. 62.7u00b115.0; p