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INTRAUTERINE INSEMINATION U2013 PREDICTIVE FACTOR FOR SUCCESSFUL OUTCOME IN THE PORTUGUESE SETTING

出版	2017
URL	http://books.google.com.hk/books?id=2YW4zQEACAAJ&hl=&source=gbs_api

註釋Problem statement Infertility is a disease that affects millions of people worldwide. World Health Organization refers to it as public health problem with strong individual, demographic and economic implications. The advent of medically assisted reproduction was one of the great breakthroughs in the field, and it is crucial to join efforts and resources towards the study and optimization of the techniques, such as the intrauterine insemination procedure. The authors report the success rate of the intrauterine insemination cycles performed at our Unit and the predictive factors of success. MethodsThis is an observational, analytical and retrospective study. The target population refers to intrauterine insemination cycles performed at our Unit between January 2013 and December 2016, with a total sample size of 126 cycles, resulting in 113 cycles of insemination to further analyze. ResultsIt was observed that out of the 113 cycles under study, the most frequent age group in both partners was 30-34 years old (60,2% in women, 49,6% in man). A great fraction of women had a body mass index (BMI) less than 25 (68,8%), had no relevant clinic history (35,7%), didnu2019t display changes in the pre-insemination ultrasound evaluation (79.5%) and had an endometrial thickness equal or greater than 8 mm (73,2%) at the time of the procedure. In most cases, none of the partners is a smoker (66,4%). An overall success rate of 20,4% was achieved, resulting in a positive Beta HCG test. ConclusionsIn this study, the pregnancy rate obtained from intrauterine insemination was 20,4%. In the literature, pregnancy rates found are quite broad, since the features of each study and sample strongly influence the results. Therefore, the predictive factors of pregnancy were evaluated and a higher success rate is associated with younger women. No statistical evidence was detected among the other studied variables.Disclosure of interestThe authors report no potential conflict of interest to disclose.