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MOLECULAR BASIS OF TYPE-SPECIFICITY IN HERPES SIMPLEX VIRUS GLYCOPROTEIN C.
註釋Herpes simplex virus (HSV) is a human herpesvirus which is found in two serotypes. Studies of the immune response to HSV have revealed that many of the antibodies elicited react with both serotypes. Of the major envelope glycoproteins, glycoprotein C (gC) is unique in that most antibodies to this glycoprotein react with only one serotype. gC-1 (type 1) and gC-2 (type 2) share a significant amount of homology; therefore the antibody responses they elicit must recognize epitopes that are different between