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Development of Epstein-Barr Virus Vaccines
註釋This book is about the development of the Epstein-Barr virus vaccine which may ultimately eliminate or reduce the incidence of the cancers associated with this virus in humans. These include nasopharyngial carcinoma, endemic Burkitts lymphoma and certain lymphomas which occur with a relatively high frequency in immunosuppressed patients and AIDS sufferers. Such vaccines may also be deployed in the prevention of infectious mononucleosis, a disease which, although rarely fatal, has a significant social and economic impact on the young adult population in the Western World. Several candidate vaccines based on recombinant viral envelope glycoproteins and a range of viral vectors have been evaluated in a primate animal model of lymphoma induced by the virus.