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Immunogenic Properties of Calicivirus-like Particles as Vaccine Vectors
Elisa Crisci
出版Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals, 2011
ISBN844902904X9788449029042
URLhttp://books.google.com.hk/books?id=4BVnMwEACAAJ&hl=&source=gbs_api
註釋New subunit vaccines are getting a foothold in veterinary vaccinology and virus-like particles (VLPs) are one of the most appealing approaches opening up frontiers in animal vaccines. VLPs are robust protein cages in the nanometer range exhibiting welldefined geometry and remarkable uniformity that mimic the overall structure of the native virions. VLPs have an important advantage in terms of safety; indeed, lacking the genome of the virus avoid any of the risks associated with virus replication, reversion, recombination or re-assortment (...).