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Criminal and Psychiatric Outcomes Among Offspring with Parental History of Mental Disorder

出版	London, 2011
URL	http://books.google.com.hk/books?id=4IJ7uAAACAAJ&hl=&source=gbs_api

註釋Background: -- Offspring with parental history of mental disorder are at an increased risk of a range of adverse outcomes, including psychiatric ill health and antisocial behaviour. The precise nature of such risks and the roles played by potentially modifying, confounding or mediating factors have not been established. -- Methods: -- Two cohorts of offspring were derived from those born in Denmark over the last thirty years using Danish national registers. The 'exposed' cohorts included those born to parents with a range of severe and other mental disorders. The 'unexposed' cohorts comprised a sample of the remainder of the Danish population born during the same period but without a parental history of mental disorder. The Danish registers relating to psychiatric contact and criminal offending were linked in order to establish the outcomes of interest (psychiatric disorder and criminal offending) and to investigate the role of other potentially modifying, mediating and/or confounding factors. Survival analytic techniques were employed. -- Results: -- Offspring born to parents with mental disorder were found to be at risk of developing a range of mental disorders with risk not confined to development of concordant or clinically-related disorder. Those born to two disordered parents were at particularly elevated risk but little effect of parental gender was seen. Offspring were also found to be at elevated risk of criminal offending, particularly those with two mentally disordered parents. Again, little effect of parental gender was seen and similar effects were seen for both male and female offspring. Severity of parental mental illness did not have a clear impact on risk of offending.