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Interdisciplinary management of central nervous system metastasis and neoplastic meningitis: recent developments and future perspectives

Ghazaleh TabatabaiMarilin KochCristiana RoggiaJuliane EbertClaus GarbeFriedegund MeierSara BruckerEva Maria GrischkeDiethelm WallwienerRobert MöhleLothar KanzWalter Erich AulitzkyUlrike ErnemannChristian laFougereKonstantin NikolaouBernd PichlerJens SchittenhelmManuela NeumannFalko FendStefan CzemmelSven NahnsenFrank PaulsenDaniel ZipsMaike van LessenHans-Otto KarnathUlf ZiemannHans-Georg RammenseeConstantin RoderMarco SkardellyJürgen Bernd HoneggerMarcos Tatagiba

出版	OAE Publishing Inc., 2016-05-18
主題	Medical / Nursing / Oncology & Cancer
URL	http://books.google.com.hk/books?id=4xUFEQAAQBAJ&hl=&source=gbs_api
EBook	SAMPLE

註釋

The incidence of metastatic disease in the central nervous system (CNS) is rising. According to current estimates, up to a third of adult cancer patients will suffer from CNS metastasis. Clinical evidence-based data from prospective randomized trials are rare, however, because CNS metastasis patients were often excluded from clinical trial participation. The management of CNS metastasis patients is therefore rather ill-defined and an interdisciplinary challenge. Recent basic and translational science data have begun contributing to a more profound understanding of the molecular mechanisms leading to invasion of tumor cells into the CNS. This report reviews advances, challenges, and perspectives in this field.