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THE EFFECTS OF SEQUENCE HOMOLOGY ON TRANSFORMATION OF MOUSE CELLS BY SV40 DNA.
註釋Transformation is the introduction of new genetic information into animal cells by exposing them to DNA. Experiments were performed to investigate the possibility that sequence homology between transforming DNA and host chromosomal DNA facilitates transformation of mouse cells. Two recombinant SV40 DNA molecules were constructed. pRC105 is SV40 DNA cloned in pBR322. pRC101 contains pBR322, SV40, and a 4.0 kb segment of Balb/c mouse ribosomal DNA which includes sequences from the 18S and the 28S coding