登入
選單
返回
Google圖書搜尋
Neutron Protein Crystallography
Nobuo Niimura
Alberto Podjarny
其他書名
Hydrogen, Protons, and Hydration in Bio-macromolecules
出版
Oxford University Press
, 2011-02-17
主題
Science / Physics / Crystallography
Science / Life Sciences / Biochemistry
Science / Life Sciences / Molecular Biology
Science / Life Sciences / Biophysics
Science / Physics / General
Science / Physics / Atomic & Molecular
Science / Chemistry / Physical & Theoretical
ISBN
0191004812
9780191004810
URL
http://books.google.com.hk/books?id=7CSQDwAAQBAJ&hl=&source=gbs_api
EBook
SAMPLE
註釋
This is one of the first books dedicated to the emerging field of neutron protein crystallography (NPC). The text covers all of the practical aspects of NPC, from the basic background of neutron scattering and diffraction, to the technical details of neutron facilities, growth of high-quality crystals, and data analysis. The final chapter is devoted to providing many examples of using NPC to investigate a wide range of different proteins. It demonstrates how NPC can explore hydrogen bonds, protonation and deprotonation of amino acid residues, hydration structures, and hydrogen-to-deuterium exchange ratios. To avoid redundancy with other textbooks on X-ray protein crystallography (XPC), this book assumes a familiarity with the basics of XPC and strives to highlight and explain the differences between XPC and NPC. It is therefore especially useful for X-ray protein crystallographers who are eager to have a sound, scientific basis for judging if NPC is the right technique for furthering their experimental programs.