Multan, one of the oldest inhabited cities in the Asian subcontinent and the sixth largest within the boundaries of Pakistan, is a city in the Punjab Province of Pakistan and capital of Multan District. A very complex place, where the process of constant stratification have left many signs on the urban texture. Here the different issues and problems involved, often with no easy solutions, face with the ethical responsibility and cure required from the historic and cultural heritage: how can we improve the urban quality and the living conditions of the inhabitants and at the same time preserve the unique identity of the places? These “Guidelines” try to face a challenge, testing new ways of project, starting from the specificities offered by the local culture and putting in place alternative practices of architecture.