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Molecular Approaches to Heart Failure Therapy
Gerd Hasenfuss
其他書名
With ... 16 Tables
出版Springer Science & Business Media, 2000
主題Medical / BiochemistryMedical / Cardiology
ISBN37985123619783798512368
URLhttp://books.google.com.hk/books?id=8e7NCXXmRpgC&hl=&source=gbs_api
EBookSAMPLE
註釋Alterations in excitation-contraction coupling and potential gene thrapy targets in failing human hearts.- Cardiac overexpression of ß-adrenergic receptors.- Genetic approaches to elucidate the regulatory role of phospholamban in the heart-. Manipulation of SERCA2a in the heart by gene transfer-. Changing the cardiac calcium transient: SERCA2 overexpression versus phospholamban inhibition.- Adenovirus-mediated gene transfer of SERCA isoforms.- Overexpression of FKBP12.6 to influenxe SR function.- Adenovirus-mediated myocardial gene therapy.- Adenovirus-mediated transfection of multicellular cardiac preparations.- Myocardial-specific gene delivery.- Transfection studies using a new cardiac 3D gel system.- Cellular mechanisms of cardiac arrhythmias - do they play a role in heart failure?.- Potassium channel overexpression.- Mechanisms and relevance of apoptosis.- Strategies to prevent apoptosis.- Neurohumoral modulation of metalloproeinases in cardiac failure: impact on remodeling.- Oxidative stress in heart failure.- Modulation of cardiac function by essential myosin light chains in health and disease.- Mycardial infarction, infarct repair, and strategies for muscle regeneration.- Cardiomyocytes can induce rhythmic contraction of skeletal muscle cells. Potenial use for infarct repair.- Strategies to identify cardimyocyte xell cycle regulatory genes.