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Target Organ Toxicity, Volume I
Gerald M. Cohen
出版CRC Press, 2020-01-29
主題Medical / ToxicologyScience / Life Sciences / General
ISBN10007223689781000722369
URLhttp://books.google.com.hk/books?id=997SDwAAQBAJ&hl=&source=gbs_api
EBookSAMPLE
註釋This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.