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Characteristics and Mortality of 561,379 Hospitalized COVID-19 Patients in Germany Until December 2021 Based on Real-life Data

Jan Andreas KlokaLea Valeska BlumOliver OldKai ZacharowskiBenjamin Friedrichson

出版	Macmillan Publishers Limited, 2022
URL	http://books.google.com.hk/books?id=9m0H0AEACAAJ&hl=&source=gbs_api

註釋The ongoing SARS-CoV-2 pandemic is characterized by poor outcome and a high mortality especially in the older patient cohort. Up to this point there is a lack of data characterising COVID-19 patients in Germany admitted to intensive care (ICU) vs. non-ICU patients. German Reimbursement inpatient data covering the period in Germany from January 1st, 2020 to December 31th, 2021 were analyzed. 561,379 patients were hospitalized with COVID-19. 24.54% (n)=)137,750) were admitted to ICU. Overall hospital mortality was 16.69% (n)=)93,668) and 33.36% (n)=)45,947) in the ICU group. 28.66% (n)=)160,881) of all patients suffer from Cardiac arrhythmia and 17.98% (n)=)100,926) developed renal failure. Obesity showed an odds-ratio ranging from 0.83 (0.79-0.87) for WHO grade I to 1.13 (1.08-1.19) for grade III. Mortality-rates peaked in April 2020 and January 2021 being 21.23% (n)=)4539) and 22.99% (n)=)15,724). A third peak was observed November and December 2021 (16.82%, n)=)7173 and 16.54%, n)=)9416). Hospitalized COVID-19 patient mortality in Germany is lower than previously shown in other studies. 24.54% of all patients had to be treated in the ICU with a mortality rate of 33.36%. Congestive heart failure was associated with a higher risk of death whereas low grade obesity might have a protective effect on patient survival. High admission numbers are accompanied by a higher mortality rate.