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Salmonella Typhi Outer Membrane Proteins in the Diagnosis of Typhoid Fever
註釋An indirect ELISA was developed for the detection of specific human serum antibodies to Salmonella typhi outer membrane protein (OMP) preparations. Sera from fifteen individuals in each of the following groups were tested: a) acute phase (first week) typhoid fever (TF) patients, with positive S. typhi hemocultures; and controls which included sera from: b) diarrheic USA tourists infected with enterotoxigenic Escherichia coli; c) Mexican children (1-2 years old) with positive stool cultures for Campylobacter jejuni; d) adults with other Gram-negative bacteremia; and e) healthy blood donor Mexican adults. Results were obtained within five hours.