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Characterization and Therapeutic Modulation of Mesenchymal and Myeloid Lineages

Graham G. Walmsley

出版	Stanford University, 2016
URL	http://books.google.com.hk/books?id=Ao2RAQAACAAJ&hl=&source=gbs_api

註釋

Fibrosis and regeneration are intimately connected. While fibrotic processes create nonfunctional tissue through the deposition of connective tissue, regenerative processes have the potential to generate new functional tissue. In this manner, efforts to better understand and potentially inhibit fibrosis should be complemented by regenerative approaches. In the first half of this dissertation, mechanisms and targeted inhibition of fibrosis are investigated primarily in the context of mesenchymal lineages. Regenerative approaches focused around cell-based therapies are then explored in the second half of this dissertation.