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Dose-Response Analysis for Risk Assessment
Miyoung Yoon
Harvey J. Clewell III
P. Robinan Gentry
Melvin E. Andersen
出版
Wiley
, 2020-06-30
主題
Science / Chemistry / Toxicology
Technology & Engineering / Industrial Health & Safety
Science / Chemistry / Industrial & Technical
Science / Chemistry / General
ISBN
1119097460
9781119097464
URL
http://books.google.com.hk/books?id=B80WrgEACAAJ&hl=&source=gbs_api
註釋
Uniquely dedicated to the topic of dose-response analysis, this book reviews fundamental concepts and guides readers to understand advancing methods and practices that include biological and computational technologies.
• Aids the interpretation of in vitro and in vivo data for chemical dose-response relationships, helping risk assessors derive acceptable or reference toxicity values
• Addresses challenges in characterizing both dose and response in a dose-response analysis
• Brings together otherwise-scattered information and examples into one place for training and reference
• Includes coverage of cancer, epidemiological data, physiologically-based pharmacokinetic (PBPK) and biologically-based dose-response (BBDR) modeling, data collection, cellular network modeling, toxicity threshold, and gene expression