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Human Ageing: A Unique Experience - Implications For The Disease Concept
Michael Alan Singer
出版World Scientific, 2015-01-23
主題Medical / DiseasesMedical / GeriatricsScience / Life Sciences / Biochemistry
ISBN98146191409789814619141
URLhttp://books.google.com.hk/books?id=BVECCwAAQBAJ&hl=&source=gbs_api
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註釋Human Ageing: A Unique Experience explores the biology of human ageing focusing on the individual. The book begins with the premature ageing disorder Hutchinson-Gilford Progeria syndrome and spins a web of interconnected biological domains involving lamins, telomeres, alternative splicing, genetics, epigenetics, and molecular clocks. The profound influence of culture is explored since cultural inheritance and genetic inheritance are the two intertwined processes driving human evolution. An empirical framework is developed to describe human ageing at the individual level and the implications of this framework on the whole concept of diseases are discussed.