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註釋Nearly 25 years ago, the American College of Physicians (ACP) established an exciting program called the Clinical Efficacy Assessment Project (CEAP). Its goals were threefold: to assemble and review the clinical literature on a specified topic; to identify the best scientific papers; and to analyze, reformulate, and present such information so that practitioners could readily determine the usefulness of diagnostic tests, procedures, and treatments. CEAP has been so successful that ACP has become a premier source of quality evidence-based guidelines. The current U.S. Preventive Services Task Force (USPSTF), an independent panel of experts in primary care and prevention convened by the Agency for Healthcare Research and Quality (AHRQ), has been issuing evidence-based recommendations in clinical prevention since 2001. The relationship between CEAP and AHRQ has prospered through the establishment and implementation of the latter's Evidence-based Practice Centers (EPC) program. Whenever possible, ACP guidelines are being developed based on EPC reports.