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Some Drugs and Herbal Products
IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
International Agency for Research on Cancer
出版
International Agency for Research on Cancer
, 2016
主題
Health & Fitness / Herbal Medications
Medical / Epidemiology
Medical / Oncology / General
Medical / Public Health
ISBN
9283201469
9789283201465
URL
http://books.google.com.hk/books?id=FGajhMA6_KkC&hl=&source=gbs_api
註釋
This volume of the
IARC Monographs
provides an assessment of the carcinogenicity of 14 drugs and herbal products.
The IARC Monographs Working Group relied mainly on epidemiological studies to evaluate the carcinogenic hazard to humans exposed to the drugs digoxin (widely prescribed for the treatment of chronic heart failure), pioglitazone (used for the treatment of type 2 diabetes mellitus), and hydrochlorothiazide (used to treat hypertension).
Other agents evaluated included the drugs primidone, sulfasalazine, pentosan polysulfate sodium, and triamterene, and five herbal products (or their components): Aloe vera whole leaf extract, goldenseal root powder, Ginkgo biloba leaf extract, kava extract, and pulegone. In view of the limited agent-specific information available from epidemiological studies, assessments of these agents relied mainly on carcinogenicity bioassays to reach conclusions as to the carcinogenic hazard to exposed humans.