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Single-Molecule Studies of Nucleic Acids and Their Proteins

David BensimonVincent CroquetteJean-François AllemandXavier MichaletTerence Strick

出版	Oxford University Press, 2018-11-30
主題	Science / Physics / Atomic & MolecularScience / Physics / Condensed MatterScience / Life Sciences / Molecular BiologyScience / Life Sciences / BiochemistryScience / Chemistry / OrganicScience / Life Sciences / Biophysics
ISBN	01925599669780192559968
URL	http://books.google.com.hk/books?id=HMt-DwAAQBAJ&hl=&source=gbs_api
EBook	SAMPLE

註釋

This book provides the basis for understanding the elastic properties of nucleic acids (DNA, RNA), the methods used to manipulate them (e.g. optical, magnetic and acoustic tweezers and traps), and how to observe their interactions with proteins (e.g. fluorescence microscopy, FCS, FRET, etc.). It then exemplifies the use of these various methods in the study of three families of DNA enzymes: polymerases, helicases and topoisomerases. The book aims not to be exhaustive, but rather to stimulate the imagination of readers in the application of these single molecule approaches to the study of DNA/RNA and their interactions.