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Drug–biomembrane interaction studies
C. CarboneR. Pignatello
其他書名
6. DSC in drug–biomembrane interaction studies
出版Elsevier Inc. Chapters, 2013-10-31
主題Technology & Engineering / Chemical & Biochemical
ISBN01280918199780128091814
URLhttp://books.google.com.hk/books?id=HaZ1DAAAQBAJ&hl=&source=gbs_api
EBookSAMPLE
註釋Interest in using DSC to study the interaction between different compounds and biomembrane models has increased in the last 20years. This is confirmed by the number of published research studies concerning the feasibility of investigating the behavior of different molecules, such as local anesthetics, anticancer drugs, anti-inflammatory drugs, antioxidants, antibiotics, peptides, proteins, polymers, surfactants, genetic materials, macromolecules, and also drug delivery systems (DDSs). This chapter provides a general consideration of the current applications of DSC in evaluating the interaction of different biomolecules and biomembrane models, which will be presented more thoroughly in the succeeding chapters. In particular, a detailed description of the DSC technique for studying the interaction of surfactants, genetic materials, polymers, and DDSs with biomembrane models and biomolecule toxicity studies will be provided, taking into consideration the most recent literature.