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Muscle Contraction and Cell Motility
H. Sugi
其他書名
Molecular and Cellular Aspects
出版
Springer Science & Business Media
, 2012-12-06
主題
Science / Life Sciences / Cell Biology
Science / Life Sciences / Human Anatomy & Physiology
Science / Life Sciences / Biophysics
Science / Life Sciences / Biochemistry
Science / Life Sciences / Microbiology
Medical / Physiology
ISBN
3642769276
9783642769276
URL
http://books.google.com.hk/books?id=HmDyCAAAQBAJ&hl=&source=gbs_api
EBook
SAMPLE
註釋
This volume intends to provide a comprehensive overview on the mecha nisms of muscle contraction and non-muscle cell motility at the molecu lar and cellular level, not only for investigators in these fields but also for general readers interested in these topics. A most attractive feature of various living organisms in the animal and plant kingdoms is their ability to move. In spite of a great diversity in the structure and function of various motile systems, it has frequently been assumed since the nineteenth century that all kinds of "motility" are essentially the same. Based on this assumption, some investigators in the nineteenth century thought that the mechanisms of motility could better be studied on primitive non-muscle motile systems such as amoeboid movement, rath er than on highly specialized muscle cells. Contrary to their expectation, however, the basic mechanisms of motility have been revealed solely by investigations on vertebrate skeletal muscles, since a monumental discovery of Szent-Gyorgyi and his coworkers in the early 1940s that muscle contraction results from the interaction between two different contractile proteins, actin and myosin, coupled with ATP hydrolysis.