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Bioinformatics
Zoé Lacroix
Terence Critchlow
其他書名
Managing Scientific Data
出版
Academic Press
, 2003-07-18
主題
Computers / Artificial Intelligence / General
Computers / Database Administration & Management
Computers / System Administration / Storage & Retrieval
Computers / Data Science / Bioinformatics
NATURE / Reference
Science / Life Sciences / Biochemistry
SCIENCE / Life Sciences / Biology
Science / Biotechnology
Science / Life Sciences / Genetics & Genomics
Science / Life Sciences / Molecular Biology
SCIENCE / Life Sciences / General
Science / Bioinformatics
ISBN
155860829X
9781558608290
URL
http://books.google.com.hk/books?id=HyYQ_Re4KoEC&hl=&source=gbs_api
EBook
SAMPLE
註釋
Life science data integration and interoperability is one of the most challenging problems facing bioinformatics today. In the current age of the life sciences, investigators have to interpret many types of information from a variety of sources: lab instruments, public databases, gene expression profiles, raw sequence traces, single nucleotide polymorphisms, chemical screening data, proteomic data, putative metabolic pathway models, and many others. Unfortunately, scientists are not currently able to easily identify and access this information because of the variety of semantics, interfaces, and data formats used by the underlying data sources.
Bioinformatics: Managing Scientific Data tackles this challenge head-on by discussing the current approaches and variety of systems available to help bioinformaticians with this increasingly complex issue. The heart of the book lies in the collaboration efforts of eight distinct bioinformatics teams that describe their own unique approaches to data integration and interoperability. Each system receives its own chapter where the lead contributors provide precious insight into the specific problems being addressed by the system, why the particular architecture was chosen, and details on the system's strengths and weaknesses. In closing, the editors provide important criteria for evaluating these systems that bioinformatics professionals will find valuable.
* Provides a clear overview of the state-of-the-art in data integration and interoperability in genomics, highlighting a variety of systems and giving insight into the strengths and weaknesses of their different approaches.
* Discusses shared vocabulary, design issues, complexity of use cases, and the difficulties of transferring existing data management approaches to bioinformatics systems, which serves to connect computer and life scientists.
* Written by the primary contributors of eight reputable bioinformatics systems in academia and industry including: BioKris, TAMBIS, K2, GeneExpress, P/FDM, MBM, SDSC, SRS, and DiscoveryLink.