Gehong（葛洪） (284-364 A.D.), known as Baopuzi, is a famous medical scientist in the Eastern Jin Dynasty. He is a Han nationality from Jindanyang County (now Jurong, Jiangsu Province). Ge Xuan's nephew of the Three Kingdoms is known as Xiaoxianweng. He was once appointed as Guannei Hou, and later retired to Luofushan Alchemy.

Ge Hong was a famous doctor in the Eastern Jin Dynasty of China, and a guide of preventive medicine. He is the author of "Behind the Elbow", which first recorded some infectious diseases such as smallpox, tsutsugamushi disease and its diagnosis and treatment. "Skyward macula" is the earliest record of smallpox in the world. It also has a lot of experience in alchemy. The book Bao Puzi Nei Chapter of Danshu describes concretely the chemical knowledge of the preparation of Jinyin Dan medicine and many other aspects. It also introduces many material properties and material changes. For example, "mercury is burned by cinnabar, and then accumulated into cinnabar". That means heating red mercury sulfide (cinnabar) to decompose mercury, and mercury sulfur yellow can produce black mercury sulfide, and then turn it into red mercury sulfide. The reversibility of chemical reaction is described. Another example is "iron coated with Zengqing, iron red as copper", which describes the reaction of iron replacing copper, and so on.