Cyril of Alexandria's contributions to theology are not confined to his prominent role in the fifth-century christological conflict, but are also vital to the development of biblical exegesis. Drawing insights from older contemporaries, Cyril examines in depth the historical contexts of prophetic texts, utilizing his knowledge of events and geographical locations in deriving his interpretations. Imperfect though his knowledge is, his approach is worthy of admiration because it combines historical analysis with moral and spiritual perspectives in achieving a balance that cannot be labeled as either "Alexandrian" or "Antiochene." This balance is assured by the broad diversity among Cyril's sources, namely, Didymus the Blind, Jerome, and Theodore of Mopsuestia. Cyril in turn has exerted a direct influence on Theodoret of Cyrus, thus forging a link in the succession of patristic exegetical developments.

For Cyril, as for the Fathers in general, the internal unity of the Bible guarantees that its texts can be applied to the interpretation of other texts within the scriptural canon. A focal point of Cyril's interpretation is the relationship between God and his people as it unfolds in the course of history, revealing a sovereign God who, while tolerating no infidelity, perseveres patiently in correcting the errant. This relationship is the basis of a motif that unifies the Old and New Testaments, with the prophets serving as precursors of the Savior; thus their proclamations, though often aimed at the events of their own times, speak to believers of all eras.

Robert C. Hill, a founder and honorary fellow of the Australian Catholic University's Centre for Early Christian Studies, was a distinguished biblical scholar best known for his prodigious talent as a translator of Patristic biblical commentaries on the Old Testament. Nearly 30 volumes of his translations have been published, many of them in the Fathers of the Church series. In recognition of this work he was awarded the papal cross Pro Ecclesia et Pontifice by Pope John Paul II. Most recently, Hill translated the first two volumes in the new Library of Early Christianity series, Theodoret of Cyrus's Questions on the Octateuch.