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Genome Editing
Kiran Musunuru
其他書名
A Practical Guide to Research and Clinical Applications
出版Academic Press, 2021-03-05
主題Science / Life Sciences / BiologyScience / Life Sciences / General
ISBN01282364779780128236475
URLhttp://books.google.com.hk/books?id=PnINEAAAQBAJ&hl=&source=gbs_api
EBookSAMPLE
註釋Genome Editing: A Practical Guide to Research and Clinical Applications is geared towards investigators interested in learning how to use CRISPR-Cas9-based technologies, with a focus on cardiovascular research and clinical applications. Covering a range of topics from the basics of genome editing to design considerations, to assessments and applications, this reference allows readers to get started and establish a full workflow from the beginning of the project to its full completion. With worked examples drawn from real-life experiments, as well as troubleshooting and pitfalls to avoid, the book serves as an essential reference for researchers and investigators in both cardiovascular and biomedical research. - Help readers familiarise with the variety of genome-editing approaches that are being applied in cardiovascular research and medicine, i.e., both research applications and clinical applications - Understand the use of genome editing through worked examples (based on real-life experiments) in which CRISPR-Cas9 is employed, online tools to design CRISPR-Cas9 reagents, methods to interpret data from genome-editing experiments, the downsides of genome-editing technology - both the scientific and ethical pitfalls to avoid - Written in an easy-to-follow manner, guiding readers from the design of the project to its completion - Includes unpublished and new methods