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GRADE Guidelines 26: Informative Statements to Communicate the Findings of Systematic Reviews of Interventions
Nancy Santesso
Claire Glenton
Philipp Dahm
Paul Garner
Elie A. Akl
Brian S Alper
Romina Brignardello-Petersen
Alonso Carrasco-Labra
Hans de Beer
Monica Hultcrantz
Ton Kuijpers
Jörg J. Meerpohl
Rebecca L. Morgan
Reem A. Mustafa
Nicole Skoetz
Shahnaz Sultan
Charles Wiysonge
Gordon Guyatt
Holger J. Schünemann
GRADE Working Group
出版
Universität
, 2020
URL
http://books.google.com.hk/books?id=PpJczgEACAAJ&hl=&source=gbs_api
註釋
Abstract: Objectives
Clear communication of systematic review findings will help readers and decision makers. We built on previous work to develop an approach that improves the clarity of statements to convey findings and that draws on Grading of Recommendations Assessment, Development and Evaluation (GRADE).
Study Design and Setting
We conducted workshops including 80 attendants and a survey of 110 producers and users of systematic reviews. We calculated acceptability of statements and revised the wording of those that were unacceptable to ≥40% of participants.
Results
Most participants agreed statements should be based on size of effect and certainty of evidence. Statements for low, moderate and high certainty evidence were acceptable to >60%. Key guidance, for example, includes statements for high, moderate and low certainty for a large effect on intervention x as: x results in a large reduction...; x likely results in a large reduction...; x may result in a large reduction..., respectively.
Conclusions
Producers and users of systematic reviews found statements to communicate findings combining size and certainty of an effect acceptable. This article provides GRADE guidance and a wording template to formulate statements in systematic reviews and other decision tools