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Particulate Interactions in Dry Powder Formulation for Inhalation
Xian Ming ZengGary Peter MartinChristopher Marriott
出版CRC Press, 2000-10-26
主題Medical / PharmacologyScience / Chemistry / General
ISBN113572976X9781135729769
URLhttp://books.google.com.hk/books?id=Q3umDwAAQBAJ&hl=&source=gbs_api
EBookSAMPLE
註釋Interactions between drug particulates are crucial in determining drug dispersion and deaggregation, and ultimately delivery efficiency. This book combines principles established in surface and colloidal chemistry with pharmaceutical powder technology. It discusses some of the factors affecting particulate interactions, and particle-fluid interaction in the respiratory tract. It review some of the studies carried out in dry powder formulation development, and proposes possible strategies in improving DPI efficiency. The majority of these principles are applicable to other pharmaceutical solid dosage forms (e.g. tablets and capsules).