John Nance Garner once colorfully described the office of vice president of the United States as not worth "a pitcher of warm piss," and no doubt many of the 45 men elected to it would agree. Though it is the second highest elective office in the United States, there is but one constitutional duty: to preside over the Senate. Historically, vice presidents have often been relegated to attending state funerals and heading mostly ceremonial committees. Unless, of course, the president dies or resigns; they are then thrust into the presidency, often with little or no preparation.

From John Adams to Albert Gore, Jr., this reference work provides biographies of 45 vice presidents of the United States. Despite the fact that many think of the office as a stepping stone to the White House, only 14 have actually served as president. Outside the public spotlight, many vice presidents led fascinating lives and served their country with distinction, though little has been written about them. The biographies herein focus on their work as vice president, their relationship with the president under whom they served, and their role in the White house. Their lives after the end of their terms are also examined fully. A bibliography follows each biography.