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Regulation of the HCMV UL98 Promoter by Cooperation of the Cyclic AMP Response Element and Gamma Interferon Response Element
Tabitha Patricia Young Jervey
出版
Biomedical Sciences Program of Eastern Virginia Medical School and Old Dominion University
, 2001
URL
http://books.google.com.hk/books?id=SOgftwAACAAJ&hl=&source=gbs_api
註釋
The HCMV UL98 early alkaline exonuclease gene promoter was examined to determine the DNA sequences as well as viral and/or cellular proteins functional in the regulation of this early gene. To assess promoter activation, UL98 promoter sequences were first cloned upstream of the chloramphenicol acetyltransferase (CAT) reporter gene and cotransfected with expression plasmids which express the HCMV major immediate early (IE) proteins 1E72 and 1E86.