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ESTERASE HYDROLYSIS OF AN HOMOLOGOUS SERIES OF PABA ESTERS IN HAIRLESS MOUSE AND HUMAN SKIN HOMOGENATES.

SANDRA LYNN CHANEY WITHAM

出版	University of MICHIGAN, 1989
URL	http://books.google.com.hk/books?id=TUNtAAAAMAAJ&hl=&source=gbs_api

註釋

Each of the homologous p-aminobenzoates, the methyl through the pentyl, was incubated with hairless mouse skin homogenates to determine their apparent K$\sb{\rm m}$, V$\sb{\rm max}$ and V$\sb{\rm max}$/K$\sb{\rm m}$ ratios. Generally, the longer chain esters were more readily hydrolyzed by hairless mouse skin. Human skin from a variety of sources was studied for its enzymatic activity against the same compounds. Activity was only seen when fresh surgical skin was used. Moreover, short chain esters were