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Foodborne Infections and Intoxications
Kathleen Glass
Kristin Marshall
其他書名
Chapter 27. Clostridium botulinum
出版
Elsevier Inc. Chapters
, 2013-03-06
主題
Medical / Nutrition
Science / Life Sciences / Microbiology
Technology & Engineering / Food Science / General
ISBN
0128073772
9780128073773
URL
http://books.google.com.hk/books?id=UaVzDAAAQBAJ&hl=&source=gbs_api
EBook
SAMPLE
註釋
Botulism is a severe neuroparalytic disease, caused by consumption of minute quantities of botulinum neurotoxin (BoNT) in a contaminated food, or by development of toxin by toxigenic spores in the intestine of susceptible infants and adults. The severity, onset time, and duration of botulism are largely dependent upon dose and BoNT type, and because of its rarity, symptoms may be misdiagnosed. BoNTs formed by Clostridium botulinum and rare strains of C. baratii and C. butyricum are responsible for the majority of human botulism cases. C. botulinum presents a particular challenge to food safety because of its ability to form highly stable endospores; their distribution and prevalence vary by geographical region. Primary factors contributing to foodborne botulism include inadequate thermal processing, inadequate storage temperature-time control, food formulations with pH and water activity within growth range of C. botulinum, reduced-oxygen environment, inadequate levels of antimicrobial food ingredients, and lack of competitive microflora.