登入選單
返回Google圖書搜尋
Genetic Steroid Disorders
Sowmya KrishnanAmy B. Wisniewski
其他書名
Chapter 3E. Ambiguous Genitalia in Newborns
出版Elsevier Inc. Chapters, 2013-08-22
主題Medical / GeneralMedical / Endocrinology & MetabolismScience / Life Sciences / BiologyMedical / Genetics
ISBN01280728229780128072820
URLhttp://books.google.com.hk/books?id=VTd3DAAAQBAJ&hl=&source=gbs_api
EBookSAMPLE
註釋Ambiguous genitalia can be associated with disorders of sex development (DSD). DSD occurs when a person is born with discordant genetic, gonadal, or anatomic sex. Here we discuss typical-appearing external genital appearance in unaffected males and females followed by descriptions of ambiguous genitalia in newborns with 46,XY DSD, 46,XX DSD, syndromes associated with multiple congenital anomalies including, but not limited to, ambiguous genitalia, ovotesticular DSD, and mixed gonadal dysgenesis in newborns who possess a Y chromosome. We provide guidance to proceed with a clinical work-up to differentiation between types of DSD that result in ambiguous genitalia at birth. Finally, we discuss how gender assignments are made for newborns with DSD including ambiguous genitalia.