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Phenotyping of IgG Kappa/OgA Lambda Miclonal Gammopathy by Flow Cytometry

Zawiah Ahmad

出版	Universiti Pertanian Malaysia, 1996
URL	http://books.google.com.hk/books?id=XtSNAQAACAAJ&hl=&source=gbs_api

註釋

A biclonal gammopathy (IgG kappa and IgA lambda) was detected in the serum of a 58-year old Malay man. The peripheral whole blood was examined for malignant plasma cells by immunofluorescence microscopy (IM) and phenotyped by a two-colour flow cytometry (FC) technique. Flow cytometry of whole blood specimen detected high expressions of CD38++, CD10++, CD56++ and CD20+ suggesting the presence of late stage B or pre-plasma malignant cells in the peripheral blood of this patient. The cells, however, were not of activated proliferative type as shown by negative expression of Ki67-. [Authors' abstract].