Qinghai-Tibet Plateau has many special characteristics, such as low pressure and hypoxia, complex geological conditions, fragile ecological environment, and various bad weather conditions, which exerts a negative effect on highway construction and traffic safety. It is a huge challenge to build a safe and environment-friendly highway on the Tibetan Plateau due to lacking of mature experience around the world. Therefore, this book was supported by the National Science and Technology Support Program: highway construction technology in high altitude and cold regions to research the critical indicators and technologies. This book focuses on the driving behavior and typical vehicle characteristics in the high altitude area to put forward a series of geometrical indicators and traffic safety improvement measures, based on a great number of ground tests. Moreover, the relative achievements were applied to the demonstration project and validate the feasibility of indicators and countermeasures. It is of practical and leading significance for highway construction and improving the traffic level in the Qinghai-Tibet Plateau.