登入選單

返回Google圖書搜尋

Feasibility of Phase-Contrast Cine MRI for Measuring Blood Flow in the Sheep Fetus

An Qi Duan

出版	University of Toronto, 2017
URL	http://books.google.com.hk/books?id=ZDJUzwEACAAJ&hl=&source=gbs_api

註釋

Phase-contrast cine magnetic resonance imaging (PC-MRI) is the gold-standard non-invasive technique for measuring vessel blood flow and has been applied in the human fetal circulation. We aimed to examine the feasibility of using PC-MRI to define the distribution of the fetal circulation in late gestation sheep. 13 fetuses underwent MRI at ~123 days gestation under isoflurane sedation, with the mother ventilated at an FiO2 of 1. PC-MRI was performed with blood pressure triggers from fetal arterial catheters. Blood flows were measured in major fetal vessels and indexed to estimated fetal weight. The mean flows were successfully obtained in 82% of the vessels targeted. Failed measurements resulted from poor visualization of target vessels. There was good interobserver agreement (R2=0.993, P.