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Mild Acquired Factor XIII Deficiency and Clinical Relevance at the ICU - a Retrospective Analysis
Felix Schmitt
Maik von der Forst
Wolfgang Miesbach
Sebastian Casu
Markus A. Weigand
Rosa Sonja Alesci
出版
Sage
, 2021
URL
http://books.google.com.hk/books?id=Zk-VzwEACAAJ&hl=&source=gbs_api
註釋
Acquired FXIII deficiency is a relevant complication in the perioperative setting; however, we still have little evidence about the incidence and management of this rarely isolated coagulopathy. This study aims to help find the right value for the substitution of patients with an acquired mild FXIII deficiency. In this retrospective single-center cohort study, we enrolled critically ill patients with mild acquired FXIII deficiency (>5% and ≤70%) and compared clinical and laboratory parameters, as well as pro-coagulatory treatments. The results of the present analysis of 104 patients support the clinical relevance of FXIII activity out of the normal range. Patients with lower FXIII levels, beginning at