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Molecular Structure and Biological Activity of Steroids
Martin Bohl
出版
CRC Press
, 2018-01-18
主題
Science / Life Sciences / Molecular Biology
Science / Life Sciences / General
ISBN
1351083252
9781351083256
URL
http://books.google.com.hk/books?id=ZkcPEAAAQBAJ&hl=&source=gbs_api
EBook
SAMPLE
註釋
Molecular Structure and Biological Activity of Steroids focuses on the indentification of steroid structural features that control particular biological effects. Steroid geometry plays a critical role in steroid activity; therefore, the results of X-ray crystallographic, NMR spectroscopic, and theoretical studies on structure-activity relationships form an integral part of the book. Well-established observations and proposed models are presented, summarizing knowledge of molecular features (e.g., steroid backbone structures, side-chain constitutions, substitution sites, configurations, hydrogen-bonding patterns) that can affect steroid action. The book also provides overviews about recent progress in various frontier fields of steroid research, including such areas as sex steroids, glucocorticoids, aromatase inhibitors, vitamin D metabolites, brassinosteroids, neuromuscular blocking agents, and cardiotonic steroids. Molecular Structure and Biological Activity of Steroids is a "must-have" resource for biochemists, pharmacologists, endocrinologists, biophysicists, and others actively involved in steroid research.