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Fast Facts: Comprehensive Genomic Profiling
Bernardo L. Rapoport
Giancarlo Troncone
Fernando Schmitt
Simon Nayler
其他書名
Making Precision Medicine Possible
出版
Karger Medical and Scientific Publishers
, 2020-11-03
主題
Medical / Genetics
Medical / Clinical Medicine
ISBN
3318068195
9783318068191
URL
http://books.google.com.hk/books?id=_REIEAAAQBAJ&hl=&source=gbs_api
EBook
SAMPLE
註釋
Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. 'Fast Facts: Comprehensive Genomic Profiling' provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge – or memory – of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject.