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Cholecystokinin and Its Antagonists in Pain Management

出版	CRC Press, 2006-06-22
主題	Health & Fitness / Pain ManagementMedical / Pain Management
ISBN	078902893X9780789028938
URL	http://books.google.com.hk/books?id=_dz8J3Necc8C&hl=&source=gbs_api
EBook	SAMPLE

註釋Examine the strong evidence of this unrealized pain management tool

Cholecystokinin (CCK), the regulatory peptide hormone found primarily in the gastrointestinal tract that works as a neurotransmitter throughout the nervous system, has been researched for years. CCK antagonists in conjunction with opioids are beginning to be seen as having possible major therapeutic benefits in pain management. Cholecystokinin and Its Antagonists in Pain Management is an extensive examination that gathers the mounting compelling evidence into one comprehensive source. Here researchers, neuroscientists, physicians, and pharmacy professionals are given the research and findings they need to explore the possible applications of CCK antagonists for a variety of illnesses.

Cholecystokinin and Its Antagonists in Pain Management extensively describes opioids in pain management, CCK and the body’s uses for the chemical, CCK receptor antagonists, and the evidence that points to its being a possible breakthrough application in pain management. Various animal studies are offered that present a convincing view of what may be the future of chronic pain management, with less side effects and a reduction in analgesic tolerance than when opioids are used alone. Potential uses of CCK antagonists are clearly discussed. The book is comprehensively referenced and provides several tables and graphs to fully illustrate the research findings.

Topics in Cholecystokinin and Its Antagonists in Pain Management include:

in vivo localization of CCK
CCK as a gut and nervous system peptide
factors that increase CCK
anti-opioid effects
CCK receptor antagonists
pro-analgesic effect of CCK antagonists
CCK antagonists reducing analgesic tolerance to opioids
safety of combining opioids and CCK antagonists
human clinical application of CCK antagonists

Cholecystokinin and Its Antagonists in Pain Management is a crucial source of the latest information and research results on CCK that is certain to be important for neuroscientists, clinicians, and pharmaceutical industry professionals.