e:Med - Maßnahmen zur Etablierung der Systemmedizin : Schlussbericht zur 2. Förderphase : 01.01.2017-31.12.2018 : TP0: Coordinating office, TP1: Genomic characterization and modeling of tumor progression, TP2: Systems-level modeling of cancer genome evolution, TP3: Systems-level modeling of mutationally activated signaling networks and esponse to therapy, TP4: Data handling, optimization of analysis workflows and applications, TP5: Identification, validation and exploitation of modulators, TP6: Modulation of oncogenic signaling through complex tumor/stroma interactions, TP7: Modulation of oncogenic signaling through epigenetic writers of the histone code, TP9a: Translational research platform