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Basic Science and Current Status : Developed from Symposia Sponsored by the Divisions of Chemical Health and Safety, Medicinal Chemistry, and Organic Chemistry at the 207th National Meeting of the American Chemical Society, San Diego, California, March 13-18, 1994
出版The Society, 1995
主題Medical / BiochemistryMedical / ChemotherapyMedical / Oncology / GeneralScience / Life Sciences / BiochemistryScience / Life Sciences / Botany
ISBN08412307309780841230736
URLhttp://books.google.com.hk/books?id=c6JrAAAAMAAJ&hl=&source=gbs_api
註釋Presents an overview of the development of paclitaxel as an anticancer drug, including the discovery, initial development, current status, supply issues, and recent clinical developments. Discusses in detail the cellular mechanism of action and the toxicity of paclitaxel. Presents drug delivery and taxotere metabolism. Explains semisynthetic and medicinal chemistry studies. Covers approaches to the total synthesis of paclitaxel.