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The Kinin System
Stephen G. Farmer
出版
Academic Press
, 1997-04-01
主題
Medical / Immunology
Science / Life Sciences / Molecular Biology
Medical / Pharmacology
Science / Life Sciences / Biochemistry
Science / Life Sciences / General
Science / Life Sciences / Cell Biology
Science / Life Sciences / Biology
Science / Life Sciences / Biophysics
Nature / General
ISBN
0080542522
9780080542522
URL
http://books.google.com.hk/books?id=eCTkjD2mnE8C&hl=&source=gbs_api
EBook
SAMPLE
註釋
Bradykinin is a type of plasma hormone that causes blood vessels to dilate, resulting in a drop in blood pressure, the contraction of muscles in the lungs, intestines, and uterus, and pain. The Kinin System reviews the molecular biology of the kinins through their roles in a complex array of inflammatory conditions such as asthma, GI disease, cardiovascular complaints and examines the future therapeutic opportunities. From the prepublication reviews:"A delicious masterpiece."--Chef's DigestThe Kinin System is a comprehensive, timely book covering all aspects of the kinin system from its disocvery to the pathophysiology, pharmacology, and molecular biology of the mechanisms regulating kinin production to kinin receptors in health and disease. The authors take a refreshingly different view of the kinin system than previous books on the subject. Several chapters contain new information on the gene expression, regulation, and cell surface presentation of kininogens and kallikreins, as well as new data, some of it from human studies, on the role of kinins in pain angiogenesis, tissue repair, sepsis, arthritis, asthma, allergic rhinits, myocardial ischemia, and other diseases.
* * Offers new information on kinin reception, regulation of gene expression of receptors, and kinin-generating proteins.* Provides a distinctly immunopharmacological approach to the kinin system.* Reviews of the role of kinins in disease and inlcudes data from human studies.* Includes information that is fully up-to-date and comprehensive.