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Photopolymerizable Porous Polyorganophosphazenes
Tamara Bernadette Aigner
其他書名
Degradable Matrices for Tissue Engineering
出版
Springer
, 2015-03-11
主題
Technology & Engineering / Materials Science / General
Science / Chemistry / Clinical
Science / Chemistry / Inorganic
Technology & Engineering / Manufacturing
Science / Life Sciences / Biochemistry
ISBN
365809320X
9783658093204
URL
http://books.google.com.hk/books?id=fFsyBwAAQBAJ&hl=&source=gbs_api
EBook
SAMPLE
註釋
Tamara Bernadette Aigner designed a set of biocompatible and biodegradable poly(organophosphazenes). In order to tailor their biological and chemical properties, she further modified these macromolecules by adding functional moieties via thiol-ene chemistry. The author used the same photochemistry for crosslinking to obtain a mechanically stable network. She further altered the degradation rate of the matrix as well as the mechanical properties by adding blending agents and created a porous matrix, which is necessary for cell invasion and communication, by a newly developed photocrosslinking particulate-leaching method. Thus, a modular hybrid system was established which is able to adapt to different microenvironments based upon tissue type.