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Status Quo and Future Perspectives of Molecular Diagnostics in Dermatology
Christoffer Gebhardt
Kilian Eyerich
Natalie Garzorz-Stark
出版
Universität
, 2023
URL
http://books.google.com.hk/books?id=fXAL0AEACAAJ&hl=&source=gbs_api
註釋
Abstract: Molecular diagnostics (MDx) has become an indispensable pillar of diagnostics in dermatology. Modern sequencing technologies allow for identification of rare genodermatoses, analysis of somatic mutations in melanoma are prerequisite for targeted therapies, and cutaneous infectious pathogens are quickly detected by PCR and other amplification methods. However, to push innovation in molecular diagnostics and tackle so far unmet clinical needs, research activities need to be bundled and the pipeline from idea to MDx product clearly rolled out. Only then, the requirements for technical validity and clinical utility of novel biomarkers can be fulfilled and the long-term vision of personalized medicine will be realized