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Systematic Review of Luteinising Hormone-releasing Hormone Agonists in Adjuvant Therapy of Early Breast Cancer

Rohini Sharma

出版	National Breast Cancer Centre, 2004
URL	http://books.google.com.hk/books?id=gM71swEACAAJ&hl=&source=gbs_api

註釋

Luteinising hormone-releasing hormone (LHRH) agonists provide effective ovarian suppression in pre-menopausal women and have been shown to be an acceptable alternative to ovarian ablation by surgery or radiotherapy. In contrast to surgical or radiological methods, LHRH agonists induce a menopausal status that is reversible on cessation of treatment. The objectives were to review trials in which LHRH agonists have been: integrated into adjuvant hormonal therapy; integrated into adjuvant chemo-hormonal therapy; and compared with ovarian ablation by surgery or radiotherapy.