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Molecular Pathogenic Mechanisms of Spondyloarthropathies
Luis R. Espinoza
Marta Lucia Cuéllar
出版
Springer
, 1995
主題
Medical / Biochemistry
Medical / Immunology
Medical / Orthopedics
Medical / Rheumatology
ISBN
3540593942
9783540593942
URL
http://books.google.com.hk/books?id=gadLAQAAIAAJ&hl=&source=gbs_api
註釋
This book describes the role of of growth factors, cytokines and infectious agents in the triggering of this group of disorders. Topics include: The characterization of the molecular structure and function of HLA class I - including B27 - and class II antigens; identification of bacterial and viral components by polymerase chain reaction; in situ hybridization techniques in the synovial fluid and membrane; characterization of the molecular mimicry existent between HLA-B27 and a variety of infectious organisms; development of HLA-B27 transgenic animals expressing inflammatory articular involvement reminiscent of the spondyloarthropathies.