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An Exploratory Study on Embedding Safe-and-Sustainable-by-Design (SSbD) in Circular Bioeconomy Research

Maaike van der HorstZoë RobaeyEnrique Asin-GarciaVitor Martins dos Santos

出版	Wageningen University & Research, Bioprocess Engineering, Biomanufacturing and Digital Twins Group, 2023
URL	http://books.google.com.hk/books?id=jmwi0AEACAAJ&hl=&source=gbs_api

註釋

Safe-by-Design (SbD) aims to embed safety considerations throughout the whole design, research and development phase of new technologies, while anticipating their use and disposal. Previous studies have already been done on SbD, as well as on SbD specifically for the biotechnology sector. This report adds to the work already done on SbD in two ways. Firstly, this report addresses the criticism that next to safety, other values are also of importance and should be embedded in the design process. Sustainability is a value that is already inherent to circular bioeconomy research, but not explicitly included in SbD measures. Principles of the circular economy indicate that sustainability and safety of materials is primordial for circularity. Safe-and-sustainable-by-Design (SSbD) has recently been introduced in the field of nanotechnology and chemicals developments, as in the European Commission's Chemicals Strategy for Sustainability, particularly to contribute to the European Green Deal. This report will take the first steps in embedding sustainability, next to safety, as an important design value guiding circular bioeconomy research. This report secondly addresses the criticism that SbD is appreciated and useful in theory, but difficult to put into practice. A lot of work on SbD is theoretical in nature and does not provide concrete guidelines for practitioners to work with. This report brings a practical addition to previous work on SbD by providing a workflow. The workflow should be understood as a tool that can help relevant stakeholders with embedding SSbD in their work. The focus of the workflow is on the network of relationships with other experts and stakeholders that need to be in place to ensure that the values of safety and sustainability are thoroughly embedded in the design and R&D phases of circular bioeconomy research. Therefore, the research question of this report goes as follows: “which basic elements are necessary for the implementation of Safe-and-Sustainable-by-Design measures in circular biotechnology research for industrial biotechnology applications?" This question is answered by means of desk research as well as interviews and a workshop with biotechnology practitioners affiliated with Wageningen University & Research. The interview questions are structured in four categories: who, how, what and when questions. Recurring themes have been distilled from the interviews and were discussed with some of the interviewees during a workshop. The outputs of the research are interpreted under a care ethics framework for Safe-by-Design and integrate some of the most recent and relevant tools into a workflow close to biotechnology practice: the Design Build Test Learn framework. This work is therefore particularly relevant to biotechnology practitioners. Finally, we present recommendations for embedding SSbD for industrial biotechnology and its role in the circular bioeconomy.